Self-assembly behavior of photomask-induced polymer/nanoparticle mixing systems was studied with cell dynamic system method based on Ginzburg-Landau theory. Effects of reaction rate, number of masks, composition ratio, concentration of nanoparticles and compatibility with polymer on morphology and structure of the system were discussed in detail. A two-dimensional phase diagram of the system structure and related parameters was constructed. Interaction mechanism and rules of components in the blend system and photomask regulation were obtained.A simple method was obtained to control pattern structure formation and transformation of the composite system. It provides references for the preparation of novel high-performance micro/nano materials.