Optimal photoassociation (PA) reactions of He+H⁺→HeH⁺ in electronic ground state, together with relevant multiphoton transition and dissociation processes, are investigated with time-dependent quantum wavepacket method. Level v=6 is set to target state and optimal PA probability of this level is obtained by optimizing laser parameters. It is shown that with increase of initial collision momentum of collision pair optimal laser duration is decreasing, but laser intensity and detuning increasing. Due to resonance multiphoton transition process, other bound levels may be resided after PA process at some collision momenta. In addition, above threshold dissociation increases linearly up to a maximum, then decrease to a saturation value and dominates dissociation processes at relative greater initial collision momentum.