CHINESE JOURNAL OF COMPUTATIONAL PHYSICS ›› 2009, Vol. 26 ›› Issue (1): 152-158.

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Monte Carlo Simulation on Topology of DNA Minicircles

LIU Yanhui1,3, HU Lin1,2   

  1. 1. The Key Laboratory for Photoelectric Technology and Application of Guizhou Province, Guiyang 550025, China;
    2. Physics Department of Guizhou University, Guiyang 550025, China;
    3. The Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 100080, China
  • Received:2007-10-26 Revised:2008-04-07 Online:2009-01-25 Published:2009-01-25

Abstract: Metropolis-Monte Carlo simulation is made to investigate autocorrelation of conformation energy and tangent vectors of minicircles(less than 500 base pairs) with flexible hinges.Direct conformation information and topology of minicircle containing flexible hinges are demonstrated.It provides powerful support for the existence of flexible hinge.

Key words: DNA minicircle, metropolis-Monte Carlo simulation, flexible hinge

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